The APN pipeline encompasses the creation of animal models for the study of the genetic basis of disease; characterisation processes (genotyping and phenotyping); and curation of both biological material and data.
The APN provides Australian’s most comprehensive collection of services for the production of unique animals. We provide a pipeline of animal model infrastructure from creation through to characterization and preservation.
ES Cell to Mouse
CRISPR gene editing
ENU Mutagenesis
Collaborative Cross mouse strains
Tools for the systematic analysis of mouse models are available.
DNA Sequencing
High-throughput quantitative protein phenotyping (RNAi)
Histopathology
Proper curation is fundamental to ensuring that good quality data is aggregated and discoverable. The APN provides:
Australian Phenome Bank
Cryopreservation services
Data Management
The purpose of the APN is to make otherwise inaccessible infrastructure available and affordable to Australian biomedical researchers. The APN teams at each node will work with researchers to ensure researchers get the best result achievable for their project and their budget. They can also help researchers discover and access other appropriate services in the APN infrastructure “pipeline” and indeed, national NCRIS-funded infrastructure generally. Contact the APN CEO or an APN service provider to discuss your requirements.